At 10:00, in St Peter's Square, Pope Leo XIV holds the Wednesday General Audience, continuing the cycle of catechesis on the documents of the Second Vatican Council with a reflection on the third chapter of the first part of the pastoral constitution «Gaudium et spes», dedicated to human activity in the universe. The Pope recalls that «for believers one thing is certain: individual and collective human activity corresponds to God's intentions» (GS 34) and that technical-scientific progress, to become authentic human progress, must be «animated and guided by charity». Among the groups present is a delegation of around 400 pilgrims from the Diocese of Rimini, led by Bishop Nicolò Anselmi, who came to Rome to thank the Pontiff for his pastoral visit to the city on 22 August 2026 and for the opening of the new diocesan pastoral year. The group, which travelled in five coaches and numerous private cars, displays a banner in the square reading «Thank you, Pope Leo!» and presents the Pope with several symbolic gifts from the area, including a book on the Malatesta Temple, a ceramic work by the local Confartigianato association, a lifeguard's uniform, the mitre made for the August visit, and a red-and-white Rimini Calcio football jersey. All participants wear a light-blue cap to be recognisable as a group. At midday the pilgrims from Rimini take part in a Holy Mass in St Peter's Basilica presided over by their Bishop, who stressed his wish that the August visit «continue to generate life, prayer, communion and attention to people». The visit forms part of the diocese's preparations for the pastoral assembly scheduled for 4 October and the start of the new pastoral year. At the end of the catechesis, in his greetings in Italian, the Pope recalls that the following day, in Saint Louis, United States, Bishop Fulton Sheen is beatified, pointing to his example as an evangelizer through the media of his time. He then makes an urgent appeal for the 112th World Day of Migrants and Refugees (27 September), dedicated this year to migrant children: «I appeal to everyone's sense of responsibility: let each of us feel involved in the lives of these children, who must always be protected and assisted», denouncing the «violence, torture, exploitation, traumatic conditions» that many of them face along migration routes, where «not infrequently they lose their lives», and the dignity «too often trampled» even in the places where they arrive. There follow the apostolic blessing for the faithful and pilgrims present in the square, among them the Minister-President of the German federal state of Saxony.